姚建铨院士科研团队在Applied Optics期刊发表最新研究成果

作者: 时间:2019-02-25 点击数:

近日,由我校特聘院士姚建铨、光电工程学院梁兰菊教授共同指导, 我校联合培养博士研究生陆宇颖在太赫兹生物传感器件方面的研究工作取得新进展,相关成果发表在国际期刊“Applied Optics”上。梁兰菊教授为文章的通讯作者,陆宇颖博士为第一作者。该成果由枣庄学院、天津大学合作完成

团队设计的椭圆金属环太赫兹高阶模生物传感器实现了对肺癌细胞A549浓度的检测,通过施加抗癌药物甲氨蝶呤,监控了A549细胞在不同抗癌药物浓度及不同药物作用时间下的凋亡过程,并证明高阶模fano共振的灵敏度比较低价模fano共振的灵敏度高。上述研究成果将在太赫兹生物医学检测等方面具有重要的应用前景

上述研究成果得到了国家重点研发计划项目(2017YFA0700202, 2017YFB1401203)、国家自然科学基金(61701434, 61735010)、山东省自然科学基金(ZR2017MF005,ZR2018LF001 )、枣庄市自主创新及成果转化项目基金(2016GH19, 2016GH31)、山东省高等学校科技计划项目基金(J17KA087)等项目的资助


Fig 1(a)The geometric size of the unit cell for the proposed metamaterial (b)the lateral view of the unit cell (c) the schematic of the metamaterials composed of periodic unit cells (d)Micrograph of the proposed biosensior with cell analyte A549 at a cell concentration of 5×105 cell/ml

Fig 6(a) Micrograph of the proposed biosensior with cell analyte A549 at a cell concentration of 5×105 cell/ml and under the condition of drug concentration 90 uM

Fig 6(b)Micrograph of the proposed biosensior with cell analyte A549 at a cell concentration of 5×105 cell/ml and under the condition of drug concentration 120 uM

Fig 6(c) The measured transmission spectra of the designed MMs-based biosensors under different drug concentration, bare (no drug), 90 uM, 120 uM, respectively.

Fig 6(d) The magnified measured transmission spectra of dip A for the designed MMs-based biosensors under different drug concentration, bare, 90 uM, 120 uM, respectively.



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